dr inż. Anna Deręgowska
- Jednostka:
Instytut Biotechnologii - Budynek: A0
- Pokój: 323 B1
- Nr telefonu: 17 851 85 20
- Email: [email protected]
- ORCID: 0000-0001-5354-3365
- Konsultacje dla studentów: poniedziałek 10:00-11:30
Informacje
Tematyka badawcza obejmuje biotechnologię medyczną, biologię nowotworów, niestabilność genetyczną.
Publikacje
- [współaut.] Kaniuka O, Bandura Y, Sabadashka M [et al.] Upregulation of GRP78 is accompanied by decreased antioxidant response and mitophagy promotion in streptozotocin-induced type 1 diabetes in rats. - Biochimica et Biophysica Acta-Molecular Basis of Disease, 2025, Vol. 1871, iss.1
- [współaut.] Rzeszutek I, Cybularczyk-Cecotka M, Stec P [et al.] New Mitochondria-Targeted Fisetin Derivative Compromises Mitophagy and Limits Survival of Drug-Induced Senescent Breast Cancer Cells. - Journal of Medicinal Chemistry, 2024, Vol. 67, iss. 19, p. 17676-17689
- [współaut.] Tomaszek N, Cuch P, Kozioł K [et al.] Glucotoxicity is mediated by cytoplasmic distribution of RAP1 in pancreatic β-cells. - Archives of Biochemistry and Biophysics, 2024, Vol. 755
- [współaut.] Hudecki A, Rzeszutek I, Lewińska A [et al.] Electrospun fiber-based micro- and nano-system for delivery of high concentrated quercetin to cancer cells. - Biomaterials Advances, 2023, Vol. 153
- [współaut.] Lewińska A, Warzybok A, Stokłosa T [et al.] Telomere loss is accompanied by decreased pool of shelterin proteins TRF2 and RAP1, elevated levels of TERRA and enhanced glycolysis in imatinib-resistant CML cells. - Toxicology in Vitro, 2023, Vol. 90
- [współaut.] Pępek M, Solarska I, Machnicki M [et al.] The interplay between telomeric complex members and BCR::ABL1 oncogenic tyrosine kinase in the maintenance of telomere length in chronic myeloid leukemia / bibliogr., streszcz. ang.. - Journal of Cancer Research and Clinical Oncology, 2023, Vol. 149, iss. 10$p. 7103-7112
- [współaut.] Przybylski P, Lewińska A, Rzeszutek I [et al.] Mutation Status and Glucose Availability Affect the Response to Mitochondria - Targeted Quercetin Derivative in Breast Cancer Cells. - Cancers, 2023, Vol. 15, iss. 23
- [współaut.] Wróbel K, Betlej G, Walczak M [et al.] Cytarabine and dexamethasone-PAMAM dendrimer di-conjugate sensitizes human acute myeloid leukemia cells to apoptotic cell death. - Journal of Drug Delivery Science and Technology, 2023, Vol. 81
- [współaut.] Domin A, Ząbek T, Kwiatkowska A [et al.] The Identification of a Novel Fucosidosis-Associated FUCA1 Mutation : a Case of a 5-Year-Old Polish Girl with Two Additional Rare Chromosomal Aberrations and Affected DNA Methylation Patterns. - Genes, 2021, Vol. 12, iss. 1
- [współaut.] Wnuk M RAP1/TERF2IP-A multifunctional player in cancer development. - Cancer, 2021, Vol. 13, iss. 23
- [współaut.] Pepek M, Pruszczyk K, Machnicki M [et al.] Differential Regulation of Telomeric Complex by BCR-ABL1 Kinase in Human Cellular Models of Chronic Myeloid Leukemia - From Single Cell Analysis to Next-Generation Sequencing. - Genes, 2020, Vol. 11, iss. 10, 1145
- [współaut.] Lewińska A, Klukowska-Rötzler J, Adamczyk-Grochala J [et al.] c-Myc activation promotes cofilin-mediated F-actin cytoskeleton remodeling and telomere homeostasis as a response to oxidant-based DNA damage in medulloblastoma cells. - Redox Biology, 2019, Vol. 24
- [współaut.] Schwarzbacherova V, Wnuk M, Holečková B [et al.] In vitro exposure to thiacloprid-based insecticide formulation promotes oxidative stress, apoptosis and genetic instability in bovine lymphocytes. - Toxicology in Vitro, 2019, Vol. 61, art. no. 104654
- [współaut.] Lewińska A, Adamczyk-Grochala J, Kwaśniewicz E [et al.] Reduced levels of methyltransferase DNMT2 sensitize human fibroblasts to oxidative stress and DNA damage that is accompanied by changes in proliferation-related miRNA expression. - Redox Biology, 2018, Vol. 14, s. 20-34
- [współaut.] Lewińska A, Adamczyk-Grochala J, Kwaśniewicz E [et al.] Diosmin-induced senescence, apoptosis and autophagy in breast cancer cells of different p53 status and ERK activity. - Toxicology Letters, 2017, Vol. 265, s. 117-130
- [współaut.] Lewińska A, Adamczyk-Grochala J, Kwaśniewicz E [et al.] Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells. - Apoptosis, 2017, Vol. 22, iss. 6, s. 800-815
- [współaut.] Lewińska A, Adamczyk-Grochala J, Wnuk M Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells. - Theranostics, 2017, Vol. 7, nr 14, pp 3461-3477
- [współaut.] Adamczyk-Grochala J, Panek A, Golec E [et al.] Affected chromosome homeostasis and genomic instability of clonal yeast cultures. - Current Genetics, 2016, Vol. 62, iss. 2, s. 405-418
- [współaut.] Adamczyk-Grochala J, Potocki L, Kuna E [et al.] Relationships between rDNA, Nop1 and Sir complex in biotechnologically relevant distillery yeasts. - Archives of Microbiology, 2016, Vol. 198, iss. 7, s. 715-723
- [współaut.] Adamczyk-Grochala J, Skoneczny M, Skoneczna A [et al.] Adaptive response to chronic mild ethanol stress involves ROS, sirtuins and changes in chromosome dosage in wine yeasts. - Oncotarget, 2016, Vol. 7, iss. 21, s. 29958-29976
- [współaut.] Adamczyk-Grochala J, Skoneczny M, Skoneczna A [et al.] Copy number variations of genes involved in stress responses reflect the redox state and DNA damage in brewing yeasts. - Cell Stress and Chaperones, 2016, Vol. 21, iss. 5, s. 849-864
- [współaut.] Adamczyk-Grochala J, Kwiatkowska A, Gurgul A [et al.] Shifts in rDNA levels act as a genome buffer promoting chromosome homeostasis. - Cell cycle, 2015, Vol. 14, iss. 21, s. 3475-3487
- [współaut.] Skoneczny M, Adamczyk-Grochala J, Kwiatkowska A [et al.] Genome-wide array-CGH analysis reveals YRF1 gene copy number variation that modulates genetic stability in distillery yeasts. - Oncotarget, 2015, Vol. 6, nr 31, s. 30650-30663
- [współaut.] Wnuk M, Miedziak B, Kułak K [et al.] Single-cell analysis of aneuploidy events using yeast whole chromosome painting probes (WCPPs). - Journal of Microbiological Methods, 2015, Vol. 11, s. 40-49
- [współaut.] Wnuk M, Panek A, Golec E [et al.] Genetic profiling of yeast industrial strains using in situ comparative genomic hybridization (CGH). - Journal of Biotechnology, 2015, Vol. 210, s. 52-56
- [współaut.] Stokłosa T, Drzewińska-Chanko J, Barankiewicz J [et al.] Effects of first and next-generation tyrosine kinase inhibitors on telomere-mediated chromosomal instability in chronic myeloid leukemia Cells. - Blood, 2014, Vol. 124, iss. 21, s. 5510
- [współaut.] Worek M, Kwiatkowska A, Ciesielska A [et al.] Identification of dermatophyte species using genomic in situ hybridization (GISH). - Journal of Microbiological Methods, 2014, Vol. 100, s. 32-41