dr hab. Renata Zadrąg-Tęcza, prof. UR
- Jednostka:
Instytut Biologii - Budynek: D9
- Pokój: 413
- Nr telefonu: +48 17 785 5413
- Email: [email protected]
- ORCID: 0000-0001-5073-9274
- Konsultacje dla studentów: Wtorek 9.00 - 10.30
Informacje
Research interests:
- The mechanisms of cell size regulation and cell growth control
- The relationship between the size and proliferative capacity of the cell
- The role of cell size in regulating different stages of cell life, i.e. the reproductive and the post-reproductive stages, and also the total lifespan of the cells
- The mechanisms of metabolic adaptation for cell growth and proliferation in calorie-deficient and calorie-excess conditions
- The contribution of increased size to cell physiological efficiency and senescence
Publikacje
- [współaut.] Kwolek-Mirek M, Maślanka R, Bednarska S [et al.] Strategies to Maintain Redox Homeostasis in Yeast Cells with Impaired Fermentation-Dependent NADPH Generation. - International Journal of Molecular Sciences, 2024, Vol. 25, iss. 17
- [współaut.] Maślanka R, Bednarska S Virtually identical does not mean exactly identical : Discrepancy in energy metabolism between glucose and fructose fermentation influences the reproductive potential of yeast cells. - Archives of Biochemistry and Biophysics, 2024, Vol. 756
- [współaut.] Maślanka R, Przywara M, Janeczko A Microbial cell autofluorescence as a method for measuring the intracellular content of B2 and B6 vitamins. - International Journal for Vitamin and Nutrition Research, 2024, Vol. 94, iss. 5-6, p. 334-341
- [współaut.] Stańczyk M, Szubart N, Maślanka R Mitochondrial Dysfunctions : Genetic and Cellular Implications Revealed by Various Model Organisms. - Genes, 2024, Vol. 15, iss. 9
- [współaut.] Kwolek-Mirek M, Maślanka R, Graboś D [et al.] Oxidative aspect of vanillin toxicity in the Saccharomyces cerevisiae yeast cells W: 48th Annual Conference on Yeasts : Slovakia, Smolenice 14-17 May 2024 : abstracts / ed. Milan Čertík. Smolenice, Institute of Chemistry, Slovak Academy of Sciences: 2024, p. 79
- [współaut.] Kwolek-Mirek M, Maślanka R, Mołoń M [et al.] L-carnosine affects the cellular redox homeostasis and reproductive potential of yeast cells growing on glucose and glycerol W: 48th Annual Conference on Yeasts : Slovakia, Smolenice 14-17 May 2024 : abstracts / ed. Milan Čertík. Smolenice, Institute of Chemistry, Slovak Academy of Sciences: 2024, p. 81
- [współaut.] Maślanka R, Bednarska S, Kwolek-Mirek M Cellular and molecular effects of vanillin using the yeast Saccharomyces cerevisiae model system W: 48th Annual Conference on Yeasts : Slovakia, Smolenice 14-17 May 2024 : abstracts / ed. Milan Čertík. Smolenice, Institute of Chemistry, Slovak Academy of Sciences: 2024, p. 80
- [współaut.] Janeczko A, Przywara M, Maślanka R [et al.] Redox perturbations in yeast cells lacking glutathione reductase. - Fungal Genetics and Biology, 2023, Vol. 167
- [współaut.] Kwolek-Mirek M, Bednarska S, Dublicka-Lisowska A [et al.] Unbalance between Pyridine Nucleotide Cofactors in The SOD1 Deficient Yeast Saccharomyces cerevisiae Causes Hypersensitivity to Alcohols and Aldehydes. - International Journal of Molecular Sciences, 2023, Vol. 24, iss. 1
- [współaut.] Kwolek-Mirek M, Dublicka-Lisowska A, Bednarska S [et al.] Changes in a Protein Profile Can Account for the Altered Phenotype of the Yeast Saccharomyces cerevisiae Mutant Lacking the Copper-Zinc Superoxide Dismutase. - Metabolites, 2023, Vol. 13, iss. 3
- [współaut.] Maślanka R Different life strategies in genetic backgrounds of the Saccharomyces cerevisiae yeast cells. - Fungal Biology, 2022, Vol. 126, iss. 8, p. 498-510
- [współaut.] Biliński T, Bylak A, Kukuła K Senescence as a trade-off between successful land colonisation and longevity : critical review and analysis of a hypothesis. - PeerJ, 2021, Vol. 9
- [współaut.] Maślanka R Wieloaspektowa rola glukozy i jej metabolizmu w regulacji parametrów fizjologicznych i potencjału reprodukcyjnego komórek na podstawie badań z użyciem drożdży Saccharomyces cerevisiae. - Postępy Biochemii, 2021, T. 67, nr 1, s. 1-15
- [współaut.] Maślanka R Reproductive Potential of Yeast Cells Depends on Overall Action of Interconnected Changes in Central Carbon Metabolism, Cellular Biosynthetic Capacity, and Proteostasis. - International Journal of Molecular Sciences, 2020, Vol. 21, iss. 19
- [współaut.] Maślanka R, Kwolek-Mirek M Linkage between Carbon Metabolism, Redox Status and Cellular Physiology in the Yeast Saccharomyces cerevisiae Devoid of SOD1 or SOD2 Gene. - Genes, 2020, Vol. 11, iss. 7
- [współaut.] Maślanka R Less is more or more is less : Implications of glucose metabolism in the regulation of the reproductive potential and total lifespan of the Saccharomyces cerevisiae yeast. - Journal of Cellular Physiology, 2019, Vol. 234, iss. 10, s. 17622-17638
- [współaut.] Kwolek-Mirek M, Alabrudzińska M, Skoneczna A Cell Size Influences the Reproductive Potential and Total Lifespan of the Saccharomyces cerevisiae Yeast as Revealed by the Analysis of Polyploid Strains. - Oxidative Medicine and Cellular Longevity, 2018, 17 p.
- [współaut.] Maślanka R, Kwolek-Mirek M Autofluorescence of yeast Saccharomyces cerevisiae cells caused by glucose metabolism products and its methodological implications. - Journal of Microbiological Methods, 2018, Vol. 146, s. 55-60
- [współaut.] Maślanka R, Bednarska S, Kwolek-Mirek M Response Mechanisms to Oxidative Stress in Yeast and Filamentous Fungi W: Stress Response Mechanisms in Fungi : Theoretical and Practical Aspects / edited by Marek Skoneczny. Cham, Springer: 2018, S. 1-34
- [współaut.] Biliński T, Bylak A The budding yeast Saccharomyces cerevisiae as a model organism : possible implications for gerontological studies. - Biogerontology, 2017, Vol. 18, iss. 4, p. 631-640
- [współaut.] Maślanka R, Kwolek-Mirek M Consequences of calorie restriction and calorie excess for the physiological parameters of the yeast Saccharomyces cerevisiae cells. - FEMS Yeast Research, 2017, Vol. 17, iss. 8, Article Number: fox087
- [współaut.] Biliński T Yeast Ageing : Reproduction Strategies Determine the Longevity of Budding and Fission Yeasts W: The Evolution of Senescence in the Tree of Life / Richard P. Shefferson, Owen Roger Jones, Roberto Salguero-Gomez (Herausgeber). Cambridge, Cambridge University Press: 2017, S. 362-380
- [współaut.] Maślanka R Glukoza - substancja o istotnym znaczeniu dla prawidłowego funkcjonowania komórki i organizmu W: Wybrane substancje o znaczeniu biologicznym : spojrzenie młodych naukowców : monografia 2017 / redakcja Magdalena Kwolek-Mirek, Mateusz Mołoń. Kraków, Creativetime: 2017, S. 108-115
- [współaut.] Biliński T, Bylak A Principles of alternative gerontology. - Aging-US, 2016, Vol. 8, no. 4, p. 589-602
- [współaut.] Kwolek-Mirek M, Mołoń M, Kaszycki P L-carnosine enhanced reproductive potential of the Saccharomyces cerevisiae yeast growing on medium containing glucose as a source of carbon. - Biogerontology, 2016, Vol. 17, iss. 4, s. 737-747
- [współaut.] Maślanka R, Kwolek K, Kwolek-Mirek M The Effect of Berry Juices on the Level of Oxidative Stress in Yeast Cells Exposed to Acrylamide. - Journal of Food Biochemistry, 2016, vol. 40, iss. 5, pp. 686-695
- [współaut.] Mołoń M Effect of temperature on replicative aging of the budding yeast Saccharomyces cerevisiae. - Biogerontology, 2015, Vol. 17, iss. 4, s. 347-357
- [współaut.] Mołoń M The links between hypertrophy, reproductive potential and longevity in the Saccharomyces cerevisiae yeast. - Acta Biochimica Polonica, 2016, vo. 63, iss. 2, s. 329-334
- [współaut.] Mołoń M, Szajwaj M, Tchórzewski M [et al.] The rate of metabolism as a factor determining longevity of the Saccharomyces cerevisiae yeast. - Age, 2016, vol. 38, no. 1, pp. 1-15
- [współaut.] Skoneczna A Reproductive potential and instability of the rDNA region of the Saccharomyces cerevisiae yeast : Common or separate mechanisms of regulation?. - Experimental Gerontology, 2016, Vol. 84, s. 29-39
- [współaut.] Biliński T, Bylak A Principles of alternative gerontology W: Future of ageing : 10th European Congress of Biogerontology and 6th Biogerontological Meeting at the Nencki Institute, Warsaw, Poland, September 23-24, 2016 : book of abstracts. Warsaw: 2016, L14
- [współaut.] Biliński T, Paszkiewicz T Energy excess is the main cause of accelerated aging of mammals. - Oncotarget, 2015, Vol. 6, iss. 15, s. 12909-12919
- [współaut.] Kwolek-Mirek M, Bednarska S, Bartosz G Acrolein-induced oxidative stress and cell death exhibiting features of apoptosis in the yeast Saccharomyces cerevisiae deficient in SOD1. - Cell Biology and Biophysics, 2015, Vol. 71, iss. 3, s. 1525-1536
- [współaut.] Maślanka R Duplikacja DNA - mechanizm rozwoju nowej funkcjonalności genów. - Postępy Biochemii, 2015, t. 61, nr 4, s. 388 - 397
- [współaut.] Mołoń M, Biliński T The longevity in the yeast Saccharomyces cerevisiae : a comparison of two approaches for assessment the lifespan. - Biochemical and Biophysical Research Communications, 2015, Vol. 460, Iss. 3, s. 651-656
- [współaut.] Maślanka R Morfologiczne zmiany struktur wewnątrzkomórkowych jako efekt delecji genów kodujących białka rybosonalne w komórkach drożdży W: Wyzwania naukowców we współczesnym świecie : monografia / redakcja naukowa Agnieszka Synowiec. Częstochowa, Omnibuss: 2015, S. 42-50
- [współaut.] Biliński T The rules of aging: are they universal? Is the yeast model relevant for gerontology?. - Acta Biochimica Polonica, 2014, Vol. 61, no. 4, s. 663-669
- [współaut.] Kwolek-Mirek M Comparison of methods used for assessing the viability and vitality of yeast cells. - FEMS Yeast Research, 2015, Vol. 14, iss. 1, s. 1068-1079
- [współaut.] Mołoń M, Mamczur J, Biliński T Dependence of the yeast Saccharomyces cerevisiae post-reproductive lifespan on the reproductive potential. - Acta Biochimica Polonica, 2013, vol. 60, nr 1, s. 111-115
- [współaut.] Kwolek-Mirek M Assessment of acrolein-induced cellular damage in the yeast saccharomyces cerevisiae cells using microscopy techniques W: XIIIth Conference on Risk Factors of Food Chain, Gödöllö - Hungary, 24-26 October 2013 : book of abstracts. Gödöllö: 2013, Abstr. nr 58
- [współaut.] Kwolek-Mirek M Effects of antioxidants on acrolein-induced oxidative protein damage in the yeast saccharomyces cerevisae W: XIIIth Conference on Risk Factors of Food Chain, Gödöllö - Hungary, 24-26 October 2013 : book of abstracts. Gödöllö: 2013, Abstr. nr 36
- [współaut.] Biliński T, Bartosz G Hypertrophy hypothesis as an alternative explanation of the phenomenon of replicative aging of yeast. - FEMS Yeast Research, 2012, vol. 12, iss. 1, p. 97-101
- [współaut.] Kwolek-Mirek M, Bartosz G Ascorbate and thiol antioxidants abolish sensitivity of yeast Saccharomyces cerevisiae to disulfiram. - Cell Biology and Toxicology, 2012, Vol. 28, nr 1, p. 1-9
- [współaut.] Kwolek-Mirek M, Bednarska S, Bartosz G The hydrolytic activity of esterases in the yeast Saccharomyces cerevisiae is strain dependent. - Cell Biology International, 2011, vol. 35, iss. 11, p. 1111-1119
- [współaut.] Kwolek-Mirek M, Bednarska S, Bartosz G Yeast Saccharomyces cerevisiae devoid of Cu, Zn-superoxide dismutase as a cellular model to study acrylamide toxicity. - Toxicology in Vitro, 2011, Vol. 25, iss. 2, p. 573-579
- [współaut.] Kwolek-Mirek M, Bartosz G, Biliński T Cell volume as a factor limiting the replicative lifespan of the yeast Saccharomyces cerevisiae. - Biogerontology, 2009, vol. 10, no. 4, p. 481-488
- [współaut.] Bartosz G, Biliński T Is the yeast a relevant model for aging of multicellular organisms? : an insight from the total lifespan of Saccharomyces cerevisiae. - Current Aging Science, 2008, Vol. 1, iss. 3
- [współaut.] Kwolek-Mirek M, Bartosz G, Biliński T Relationship between the replicative age and cell volume in Saccharomyces cerevisiae. - Acta Biochimica Polonica, 2006, Vol. 53, nr 4, s. 747-751
- [współaut.] Wojnar L, Bartosz G, Biliński T Does yeast shmooing mean a commitment to apoptosis?. - Cell Biology International, 2006, vol. 30, iss. 3, s. 205-209
- [współaut.] Biliński T, Bartosz G, Bartosz G [et al.] Ćwiczenia : podstawy biofizyki, chemia fizyczna, biochemia, enzymologia, biologia komórki / pod red. Tomasza Bilińskiego i Grzegorza Bartosza. Rzeszów, Uniwersytet Rzeszowski: 2006, 254 s.
- [współaut.] Żyracka E, Kozioł S, Krzepiłko A [et al.] Yeast as a biosensor for antioxidants : simple growth tests employing a Saccharomyces cerevisiae mutant defective in superoxide dismutase. - Acta Biochimica Polonica, 2005, vol. 52, no. 3, s. 679-684
- [współaut.] Żyracka E, Kozioł S, Krzepilko A [et al.] Ascorbate abolishes auxotrophy caused by the lack of superoxide dismutase in "Saccharomyces cerevisiae" : yeast can be a biosensor for antioxidants. - Journal of Biotechnology, 2005, vol. 115, iss. 3, s. 271-278
- [współaut.] Bartosz G, Biliński T Replicative aging of the yeast does not require DNA replication. - Biochemical and Biophysical Research Communications, 2005, vol. 333, iss. 1, s. 138-141
- [współaut.] Krzepiłko A, Święciło A, Wawryn J [et al.] Ascorbate restores lifespan of superoxide-dismutase deficient yeast. - Free Radical Research, 2004, vol. 38, nr 9, s. 1019-1024